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Chest CT Findings in Coronavirus Disease-19 (COVID-19): Relationship to Duration of Infection.

Identifieur interne : 000A43 ( an2020/Analysis ); précédent : 000A42; suivant : 000A44

Chest CT Findings in Coronavirus Disease-19 (COVID-19): Relationship to Duration of Infection.

Auteurs : Adam Bernheim ; Xueyan Mei ; Mingqian Huang ; Yang Yang ; Zahi A. Fayad ; Ning Zhang ; Kaiyue Diao ; Bin Lin ; Xiqi Zhu ; Kunwei Li ; Shaolin Li ; Hong Shan ; Adam Jacobi ; Michael Chung

Source :

RBID : pubmed:32077789

Abstract

In this retrospective study, chest CTs of 121 symptomatic patients infected with coronavirus disease-19 (COVID-19) from four centers in China from January 18, 2020 to February 2, 2020 were reviewed for common CT findings in relationship to the time between symptom onset and the initial CT scan (i.e. early, 0-2 days (36 patients), intermediate 3-5 days (33 patients), late 6-12 days (25 patients)). The hallmarks of COVID-19 infection on imaging were bilateral and peripheral ground-glass and consolidative pulmonary opacities. Notably, 20/36 (56%) of early patients had a normal CT. With a longer time after the onset of symptoms, CT findings were more frequent, including consolidation, bilateral and peripheral disease, greater total lung involvement, linear opacities, "crazy-paving" pattern and the "reverse halo" sign. Bilateral lung involvement was observed in 10/36 early patients (28%), 25/33 intermediate patients (76%), and 22/25 late patients (88%).

DOI: 10.1148/radiol.2020200463
PubMed: 32077789


Affiliations:


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pubmed:32077789

Le document en format XML

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<name sortKey="Yang, Yang" sort="Yang, Yang" uniqKey="Yang Y" first="Yang" last="Yang">Yang Yang</name>
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<name sortKey="Zhang, Ning" sort="Zhang, Ning" uniqKey="Zhang N" first="Ning" last="Zhang">Ning Zhang</name>
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<name sortKey="Zhu, Xiqi" sort="Zhu, Xiqi" uniqKey="Zhu X" first="Xiqi" last="Zhu">Xiqi Zhu</name>
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<nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (A.B., M.H., Y.Y., A.J., M.C); BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY (X.M); Department of Diagnostic, Molecular and Interventional Radiology, and BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York (Z.A.F); Department of Radiology, The First Affiliated Hospital of Nanchang University, NanChang, JiangXi, China (N.Z); Department of Radiology, West China Hospital, Sichuan University, Chengdu Sichuan, China (K.D); Department of Radiology, The Second Affiliated Hospital of Zhejiang University School Medicine, Hangzhou, China (B.L); Department of Radiology, Nanxishan Hospital, Guangxi Zhuang Autonomous Region, China (X.Z); Department of Radiology, The Fifth Affiliated Hospital, Sun Yat-sen University, New Xiangzhou, Zhuhai, Guangdong Province, China (K.L., S.L., H.S).</nlm:affiliation>
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<name sortKey="Li, Kunwei" sort="Li, Kunwei" uniqKey="Li K" first="Kunwei" last="Li">Kunwei Li</name>
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<nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (A.B., M.H., Y.Y., A.J., M.C); BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY (X.M); Department of Diagnostic, Molecular and Interventional Radiology, and BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York (Z.A.F); Department of Radiology, The First Affiliated Hospital of Nanchang University, NanChang, JiangXi, China (N.Z); Department of Radiology, West China Hospital, Sichuan University, Chengdu Sichuan, China (K.D); Department of Radiology, The Second Affiliated Hospital of Zhejiang University School Medicine, Hangzhou, China (B.L); Department of Radiology, Nanxishan Hospital, Guangxi Zhuang Autonomous Region, China (X.Z); Department of Radiology, The Fifth Affiliated Hospital, Sun Yat-sen University, New Xiangzhou, Zhuhai, Guangdong Province, China (K.L., S.L., H.S).</nlm:affiliation>
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<name sortKey="Li, Shaolin" sort="Li, Shaolin" uniqKey="Li S" first="Shaolin" last="Li">Shaolin Li</name>
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<nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (A.B., M.H., Y.Y., A.J., M.C); BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY (X.M); Department of Diagnostic, Molecular and Interventional Radiology, and BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York (Z.A.F); Department of Radiology, The First Affiliated Hospital of Nanchang University, NanChang, JiangXi, China (N.Z); Department of Radiology, West China Hospital, Sichuan University, Chengdu Sichuan, China (K.D); Department of Radiology, The Second Affiliated Hospital of Zhejiang University School Medicine, Hangzhou, China (B.L); Department of Radiology, Nanxishan Hospital, Guangxi Zhuang Autonomous Region, China (X.Z); Department of Radiology, The Fifth Affiliated Hospital, Sun Yat-sen University, New Xiangzhou, Zhuhai, Guangdong Province, China (K.L., S.L., H.S).</nlm:affiliation>
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<name sortKey="Shan, Hong" sort="Shan, Hong" uniqKey="Shan H" first="Hong" last="Shan">Hong Shan</name>
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<nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (A.B., M.H., Y.Y., A.J., M.C); BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY (X.M); Department of Diagnostic, Molecular and Interventional Radiology, and BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York (Z.A.F); Department of Radiology, The First Affiliated Hospital of Nanchang University, NanChang, JiangXi, China (N.Z); Department of Radiology, West China Hospital, Sichuan University, Chengdu Sichuan, China (K.D); Department of Radiology, The Second Affiliated Hospital of Zhejiang University School Medicine, Hangzhou, China (B.L); Department of Radiology, Nanxishan Hospital, Guangxi Zhuang Autonomous Region, China (X.Z); Department of Radiology, The Fifth Affiliated Hospital, Sun Yat-sen University, New Xiangzhou, Zhuhai, Guangdong Province, China (K.L., S.L., H.S).</nlm:affiliation>
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<name sortKey="Jacobi, Adam" sort="Jacobi, Adam" uniqKey="Jacobi A" first="Adam" last="Jacobi">Adam Jacobi</name>
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<nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (A.B., M.H., Y.Y., A.J., M.C); BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY (X.M); Department of Diagnostic, Molecular and Interventional Radiology, and BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York (Z.A.F); Department of Radiology, The First Affiliated Hospital of Nanchang University, NanChang, JiangXi, China (N.Z); Department of Radiology, West China Hospital, Sichuan University, Chengdu Sichuan, China (K.D); Department of Radiology, The Second Affiliated Hospital of Zhejiang University School Medicine, Hangzhou, China (B.L); Department of Radiology, Nanxishan Hospital, Guangxi Zhuang Autonomous Region, China (X.Z); Department of Radiology, The Fifth Affiliated Hospital, Sun Yat-sen University, New Xiangzhou, Zhuhai, Guangdong Province, China (K.L., S.L., H.S).</nlm:affiliation>
<wicri:noCountry code="subField">H.S).</wicri:noCountry>
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<name sortKey="Chung, Michael" sort="Chung, Michael" uniqKey="Chung M" first="Michael" last="Chung">Michael Chung</name>
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<nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (A.B., M.H., Y.Y., A.J., M.C); BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY (X.M); Department of Diagnostic, Molecular and Interventional Radiology, and BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York (Z.A.F); Department of Radiology, The First Affiliated Hospital of Nanchang University, NanChang, JiangXi, China (N.Z); Department of Radiology, West China Hospital, Sichuan University, Chengdu Sichuan, China (K.D); Department of Radiology, The Second Affiliated Hospital of Zhejiang University School Medicine, Hangzhou, China (B.L); Department of Radiology, Nanxishan Hospital, Guangxi Zhuang Autonomous Region, China (X.Z); Department of Radiology, The Fifth Affiliated Hospital, Sun Yat-sen University, New Xiangzhou, Zhuhai, Guangdong Province, China (K.L., S.L., H.S).</nlm:affiliation>
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<title xml:lang="en">Chest CT Findings in Coronavirus Disease-19 (COVID-19): Relationship to Duration of Infection.</title>
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<nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (A.B., M.H., Y.Y., A.J., M.C); BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY (X.M); Department of Diagnostic, Molecular and Interventional Radiology, and BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York (Z.A.F); Department of Radiology, The First Affiliated Hospital of Nanchang University, NanChang, JiangXi, China (N.Z); Department of Radiology, West China Hospital, Sichuan University, Chengdu Sichuan, China (K.D); Department of Radiology, The Second Affiliated Hospital of Zhejiang University School Medicine, Hangzhou, China (B.L); Department of Radiology, Nanxishan Hospital, Guangxi Zhuang Autonomous Region, China (X.Z); Department of Radiology, The Fifth Affiliated Hospital, Sun Yat-sen University, New Xiangzhou, Zhuhai, Guangdong Province, China (K.L., S.L., H.S).</nlm:affiliation>
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<name sortKey="Mei, Xueyan" sort="Mei, Xueyan" uniqKey="Mei X" first="Xueyan" last="Mei">Xueyan Mei</name>
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<nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (A.B., M.H., Y.Y., A.J., M.C); BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY (X.M); Department of Diagnostic, Molecular and Interventional Radiology, and BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York (Z.A.F); Department of Radiology, The First Affiliated Hospital of Nanchang University, NanChang, JiangXi, China (N.Z); Department of Radiology, West China Hospital, Sichuan University, Chengdu Sichuan, China (K.D); Department of Radiology, The Second Affiliated Hospital of Zhejiang University School Medicine, Hangzhou, China (B.L); Department of Radiology, Nanxishan Hospital, Guangxi Zhuang Autonomous Region, China (X.Z); Department of Radiology, The Fifth Affiliated Hospital, Sun Yat-sen University, New Xiangzhou, Zhuhai, Guangdong Province, China (K.L., S.L., H.S).</nlm:affiliation>
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<name sortKey="Huang, Mingqian" sort="Huang, Mingqian" uniqKey="Huang M" first="Mingqian" last="Huang">Mingqian Huang</name>
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<nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (A.B., M.H., Y.Y., A.J., M.C); BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY (X.M); Department of Diagnostic, Molecular and Interventional Radiology, and BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York (Z.A.F); Department of Radiology, The First Affiliated Hospital of Nanchang University, NanChang, JiangXi, China (N.Z); Department of Radiology, West China Hospital, Sichuan University, Chengdu Sichuan, China (K.D); Department of Radiology, The Second Affiliated Hospital of Zhejiang University School Medicine, Hangzhou, China (B.L); Department of Radiology, Nanxishan Hospital, Guangxi Zhuang Autonomous Region, China (X.Z); Department of Radiology, The Fifth Affiliated Hospital, Sun Yat-sen University, New Xiangzhou, Zhuhai, Guangdong Province, China (K.L., S.L., H.S).</nlm:affiliation>
<wicri:noCountry code="subField">H.S).</wicri:noCountry>
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<name sortKey="Yang, Yang" sort="Yang, Yang" uniqKey="Yang Y" first="Yang" last="Yang">Yang Yang</name>
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<nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (A.B., M.H., Y.Y., A.J., M.C); BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY (X.M); Department of Diagnostic, Molecular and Interventional Radiology, and BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York (Z.A.F); Department of Radiology, The First Affiliated Hospital of Nanchang University, NanChang, JiangXi, China (N.Z); Department of Radiology, West China Hospital, Sichuan University, Chengdu Sichuan, China (K.D); Department of Radiology, The Second Affiliated Hospital of Zhejiang University School Medicine, Hangzhou, China (B.L); Department of Radiology, Nanxishan Hospital, Guangxi Zhuang Autonomous Region, China (X.Z); Department of Radiology, The Fifth Affiliated Hospital, Sun Yat-sen University, New Xiangzhou, Zhuhai, Guangdong Province, China (K.L., S.L., H.S).</nlm:affiliation>
<wicri:noCountry code="subField">H.S).</wicri:noCountry>
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<name sortKey="Fayad, Zahi A" sort="Fayad, Zahi A" uniqKey="Fayad Z" first="Zahi A" last="Fayad">Zahi A. Fayad</name>
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<nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (A.B., M.H., Y.Y., A.J., M.C); BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY (X.M); Department of Diagnostic, Molecular and Interventional Radiology, and BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York (Z.A.F); Department of Radiology, The First Affiliated Hospital of Nanchang University, NanChang, JiangXi, China (N.Z); Department of Radiology, West China Hospital, Sichuan University, Chengdu Sichuan, China (K.D); Department of Radiology, The Second Affiliated Hospital of Zhejiang University School Medicine, Hangzhou, China (B.L); Department of Radiology, Nanxishan Hospital, Guangxi Zhuang Autonomous Region, China (X.Z); Department of Radiology, The Fifth Affiliated Hospital, Sun Yat-sen University, New Xiangzhou, Zhuhai, Guangdong Province, China (K.L., S.L., H.S).</nlm:affiliation>
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<author>
<name sortKey="Zhang, Ning" sort="Zhang, Ning" uniqKey="Zhang N" first="Ning" last="Zhang">Ning Zhang</name>
<affiliation>
<nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (A.B., M.H., Y.Y., A.J., M.C); BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY (X.M); Department of Diagnostic, Molecular and Interventional Radiology, and BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York (Z.A.F); Department of Radiology, The First Affiliated Hospital of Nanchang University, NanChang, JiangXi, China (N.Z); Department of Radiology, West China Hospital, Sichuan University, Chengdu Sichuan, China (K.D); Department of Radiology, The Second Affiliated Hospital of Zhejiang University School Medicine, Hangzhou, China (B.L); Department of Radiology, Nanxishan Hospital, Guangxi Zhuang Autonomous Region, China (X.Z); Department of Radiology, The Fifth Affiliated Hospital, Sun Yat-sen University, New Xiangzhou, Zhuhai, Guangdong Province, China (K.L., S.L., H.S).</nlm:affiliation>
<wicri:noCountry code="subField">H.S).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Diao, Kaiyue" sort="Diao, Kaiyue" uniqKey="Diao K" first="Kaiyue" last="Diao">Kaiyue Diao</name>
<affiliation>
<nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (A.B., M.H., Y.Y., A.J., M.C); BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY (X.M); Department of Diagnostic, Molecular and Interventional Radiology, and BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York (Z.A.F); Department of Radiology, The First Affiliated Hospital of Nanchang University, NanChang, JiangXi, China (N.Z); Department of Radiology, West China Hospital, Sichuan University, Chengdu Sichuan, China (K.D); Department of Radiology, The Second Affiliated Hospital of Zhejiang University School Medicine, Hangzhou, China (B.L); Department of Radiology, Nanxishan Hospital, Guangxi Zhuang Autonomous Region, China (X.Z); Department of Radiology, The Fifth Affiliated Hospital, Sun Yat-sen University, New Xiangzhou, Zhuhai, Guangdong Province, China (K.L., S.L., H.S).</nlm:affiliation>
<wicri:noCountry code="subField">H.S).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Lin, Bin" sort="Lin, Bin" uniqKey="Lin B" first="Bin" last="Lin">Bin Lin</name>
<affiliation>
<nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (A.B., M.H., Y.Y., A.J., M.C); BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY (X.M); Department of Diagnostic, Molecular and Interventional Radiology, and BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York (Z.A.F); Department of Radiology, The First Affiliated Hospital of Nanchang University, NanChang, JiangXi, China (N.Z); Department of Radiology, West China Hospital, Sichuan University, Chengdu Sichuan, China (K.D); Department of Radiology, The Second Affiliated Hospital of Zhejiang University School Medicine, Hangzhou, China (B.L); Department of Radiology, Nanxishan Hospital, Guangxi Zhuang Autonomous Region, China (X.Z); Department of Radiology, The Fifth Affiliated Hospital, Sun Yat-sen University, New Xiangzhou, Zhuhai, Guangdong Province, China (K.L., S.L., H.S).</nlm:affiliation>
<wicri:noCountry code="subField">H.S).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Zhu, Xiqi" sort="Zhu, Xiqi" uniqKey="Zhu X" first="Xiqi" last="Zhu">Xiqi Zhu</name>
<affiliation>
<nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (A.B., M.H., Y.Y., A.J., M.C); BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY (X.M); Department of Diagnostic, Molecular and Interventional Radiology, and BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York (Z.A.F); Department of Radiology, The First Affiliated Hospital of Nanchang University, NanChang, JiangXi, China (N.Z); Department of Radiology, West China Hospital, Sichuan University, Chengdu Sichuan, China (K.D); Department of Radiology, The Second Affiliated Hospital of Zhejiang University School Medicine, Hangzhou, China (B.L); Department of Radiology, Nanxishan Hospital, Guangxi Zhuang Autonomous Region, China (X.Z); Department of Radiology, The Fifth Affiliated Hospital, Sun Yat-sen University, New Xiangzhou, Zhuhai, Guangdong Province, China (K.L., S.L., H.S).</nlm:affiliation>
<wicri:noCountry code="subField">H.S).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Li, Kunwei" sort="Li, Kunwei" uniqKey="Li K" first="Kunwei" last="Li">Kunwei Li</name>
<affiliation>
<nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (A.B., M.H., Y.Y., A.J., M.C); BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY (X.M); Department of Diagnostic, Molecular and Interventional Radiology, and BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York (Z.A.F); Department of Radiology, The First Affiliated Hospital of Nanchang University, NanChang, JiangXi, China (N.Z); Department of Radiology, West China Hospital, Sichuan University, Chengdu Sichuan, China (K.D); Department of Radiology, The Second Affiliated Hospital of Zhejiang University School Medicine, Hangzhou, China (B.L); Department of Radiology, Nanxishan Hospital, Guangxi Zhuang Autonomous Region, China (X.Z); Department of Radiology, The Fifth Affiliated Hospital, Sun Yat-sen University, New Xiangzhou, Zhuhai, Guangdong Province, China (K.L., S.L., H.S).</nlm:affiliation>
<wicri:noCountry code="subField">H.S).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Li, Shaolin" sort="Li, Shaolin" uniqKey="Li S" first="Shaolin" last="Li">Shaolin Li</name>
<affiliation>
<nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (A.B., M.H., Y.Y., A.J., M.C); BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY (X.M); Department of Diagnostic, Molecular and Interventional Radiology, and BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York (Z.A.F); Department of Radiology, The First Affiliated Hospital of Nanchang University, NanChang, JiangXi, China (N.Z); Department of Radiology, West China Hospital, Sichuan University, Chengdu Sichuan, China (K.D); Department of Radiology, The Second Affiliated Hospital of Zhejiang University School Medicine, Hangzhou, China (B.L); Department of Radiology, Nanxishan Hospital, Guangxi Zhuang Autonomous Region, China (X.Z); Department of Radiology, The Fifth Affiliated Hospital, Sun Yat-sen University, New Xiangzhou, Zhuhai, Guangdong Province, China (K.L., S.L., H.S).</nlm:affiliation>
<wicri:noCountry code="subField">H.S).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Shan, Hong" sort="Shan, Hong" uniqKey="Shan H" first="Hong" last="Shan">Hong Shan</name>
<affiliation>
<nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (A.B., M.H., Y.Y., A.J., M.C); BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY (X.M); Department of Diagnostic, Molecular and Interventional Radiology, and BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York (Z.A.F); Department of Radiology, The First Affiliated Hospital of Nanchang University, NanChang, JiangXi, China (N.Z); Department of Radiology, West China Hospital, Sichuan University, Chengdu Sichuan, China (K.D); Department of Radiology, The Second Affiliated Hospital of Zhejiang University School Medicine, Hangzhou, China (B.L); Department of Radiology, Nanxishan Hospital, Guangxi Zhuang Autonomous Region, China (X.Z); Department of Radiology, The Fifth Affiliated Hospital, Sun Yat-sen University, New Xiangzhou, Zhuhai, Guangdong Province, China (K.L., S.L., H.S).</nlm:affiliation>
<wicri:noCountry code="subField">H.S).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Jacobi, Adam" sort="Jacobi, Adam" uniqKey="Jacobi A" first="Adam" last="Jacobi">Adam Jacobi</name>
<affiliation>
<nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (A.B., M.H., Y.Y., A.J., M.C); BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY (X.M); Department of Diagnostic, Molecular and Interventional Radiology, and BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York (Z.A.F); Department of Radiology, The First Affiliated Hospital of Nanchang University, NanChang, JiangXi, China (N.Z); Department of Radiology, West China Hospital, Sichuan University, Chengdu Sichuan, China (K.D); Department of Radiology, The Second Affiliated Hospital of Zhejiang University School Medicine, Hangzhou, China (B.L); Department of Radiology, Nanxishan Hospital, Guangxi Zhuang Autonomous Region, China (X.Z); Department of Radiology, The Fifth Affiliated Hospital, Sun Yat-sen University, New Xiangzhou, Zhuhai, Guangdong Province, China (K.L., S.L., H.S).</nlm:affiliation>
<wicri:noCountry code="subField">H.S).</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Chung, Michael" sort="Chung, Michael" uniqKey="Chung M" first="Michael" last="Chung">Michael Chung</name>
<affiliation>
<nlm:affiliation>Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (A.B., M.H., Y.Y., A.J., M.C); BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY (X.M); Department of Diagnostic, Molecular and Interventional Radiology, and BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York (Z.A.F); Department of Radiology, The First Affiliated Hospital of Nanchang University, NanChang, JiangXi, China (N.Z); Department of Radiology, West China Hospital, Sichuan University, Chengdu Sichuan, China (K.D); Department of Radiology, The Second Affiliated Hospital of Zhejiang University School Medicine, Hangzhou, China (B.L); Department of Radiology, Nanxishan Hospital, Guangxi Zhuang Autonomous Region, China (X.Z); Department of Radiology, The Fifth Affiliated Hospital, Sun Yat-sen University, New Xiangzhou, Zhuhai, Guangdong Province, China (K.L., S.L., H.S).</nlm:affiliation>
<wicri:noCountry code="subField">H.S).</wicri:noCountry>
</affiliation>
</author>
</analytic>
<series>
<title level="j">Radiology</title>
<idno type="eISSN">1527-1315</idno>
<imprint>
<date when="2020" type="published">2020</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc>
<textClass></textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">In this retrospective study, chest CTs of 121 symptomatic patients infected with coronavirus disease-19 (COVID-19) from four centers in China from January 18, 2020 to February 2, 2020 were reviewed for common CT findings in relationship to the time between symptom onset and the initial CT scan (i.e. early, 0-2 days (36 patients), intermediate 3-5 days (33 patients), late 6-12 days (25 patients)). The hallmarks of COVID-19 infection on imaging were bilateral and peripheral ground-glass and consolidative pulmonary opacities. Notably, 20/36 (56%) of early patients had a normal CT. With a longer time after the onset of symptoms, CT findings were more frequent, including consolidation, bilateral and peripheral disease, greater total lung involvement, linear opacities, "crazy-paving" pattern and the "reverse halo" sign. Bilateral lung involvement was observed in 10/36 early patients (28%), 25/33 intermediate patients (76%), and 22/25 late patients (88%).</div>
</front>
</TEI>
<affiliations>
<list></list>
<tree>
<noCountry>
<name sortKey="Bernheim, Adam" sort="Bernheim, Adam" uniqKey="Bernheim A" first="Adam" last="Bernheim">Adam Bernheim</name>
<name sortKey="Chung, Michael" sort="Chung, Michael" uniqKey="Chung M" first="Michael" last="Chung">Michael Chung</name>
<name sortKey="Diao, Kaiyue" sort="Diao, Kaiyue" uniqKey="Diao K" first="Kaiyue" last="Diao">Kaiyue Diao</name>
<name sortKey="Fayad, Zahi A" sort="Fayad, Zahi A" uniqKey="Fayad Z" first="Zahi A" last="Fayad">Zahi A. Fayad</name>
<name sortKey="Huang, Mingqian" sort="Huang, Mingqian" uniqKey="Huang M" first="Mingqian" last="Huang">Mingqian Huang</name>
<name sortKey="Jacobi, Adam" sort="Jacobi, Adam" uniqKey="Jacobi A" first="Adam" last="Jacobi">Adam Jacobi</name>
<name sortKey="Li, Kunwei" sort="Li, Kunwei" uniqKey="Li K" first="Kunwei" last="Li">Kunwei Li</name>
<name sortKey="Li, Shaolin" sort="Li, Shaolin" uniqKey="Li S" first="Shaolin" last="Li">Shaolin Li</name>
<name sortKey="Lin, Bin" sort="Lin, Bin" uniqKey="Lin B" first="Bin" last="Lin">Bin Lin</name>
<name sortKey="Mei, Xueyan" sort="Mei, Xueyan" uniqKey="Mei X" first="Xueyan" last="Mei">Xueyan Mei</name>
<name sortKey="Shan, Hong" sort="Shan, Hong" uniqKey="Shan H" first="Hong" last="Shan">Hong Shan</name>
<name sortKey="Yang, Yang" sort="Yang, Yang" uniqKey="Yang Y" first="Yang" last="Yang">Yang Yang</name>
<name sortKey="Zhang, Ning" sort="Zhang, Ning" uniqKey="Zhang N" first="Ning" last="Zhang">Ning Zhang</name>
<name sortKey="Zhu, Xiqi" sort="Zhu, Xiqi" uniqKey="Zhu X" first="Xiqi" last="Zhu">Xiqi Zhu</name>
</noCountry>
</tree>
</affiliations>
</record>

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